Intraventricular haemorrhage (IVH)
Bleeding from the fragile germinal matrix of the preterm brain
Overview
Bleeding into the germinal matrix/ventricles of the PRETERM brain, from the fragile immature vasculature — commonest in the first few days, especially in the very preterm/unstable infant. Graded I-IV; severe IVH causes post-haemorrhagic hydrocephalus and neurodevelopmental impairment. Detected by cranial ultrasound screening; management is supportive with monitoring for hydrocephalus.
Recognise
- Very preterm infant, usually within the first 72 hours; may be silent or present with deterioration, apnoea, seizures, a falling haematocrit, a bulging fontanelle
- Graded I-IV (IV = parenchymal involvement); risk factors: extreme prematurity, hypoxia, instability, pneumothorax
- Complication: post-haemorrhagic hydrocephalus, neurodevelopmental impairment
Red flags
- Post-haemorrhagic ventricular dilatation/hydrocephalus (expanding head, bulging fontanelle) → neurosurgical input
- Acute deterioration/seizures
Differentials & how to tell them apart
Investigations
CRANIAL ULTRASOUND (through the fontanelle — screening and grading); monitor head circumference; coagulation/haematocrit.
Management
Supportive care + cranial USS surveillance; treat post-haemorrhagic hydrocephalus
- 1Cranial ultrasound screening in preterm infants detects and grades IVH. Supportive intensive care; monitor head circumference for hydrocephalus.Gate: Prevention is about avoiding the precipitants (instability, hypoxia, pneumothorax, rapid fluid/pressure swings); severe IVH → monitor for post-haemorrhagic hydrocephalus needing neurosurgical intervention
- 2Manage hydrocephalus (reservoir/shunt); neurodevelopmental follow-up.
Key points
Very preterm + first few days + deterioration/bulging fontanelle = IVH (germinal matrix) → cranial USS. Watch for post-haemorrhagic hydrocephalus. Prevent by keeping the baby stable.
Monitor & prognosis
Cranial USS, head circumference; development.
Mild grades good; severe IVH impairs neurodevelopment.
Source: RCPCH; BAPM