Neck lumps (branchial & thyroglossal cysts)
Congenital neck cysts — framework for the neck lump
Overview
A practical framework for the neck lump, anchored on the two classic congenital cysts: a THYROGLOSSAL cyst (midline, moves up with tongue protrusion/swallowing) and a BRANCHIAL cyst (lateral, anterior to sternocleidomastoid). The overriding rule: a persistent neck lump in an adult is malignancy/metastasis until proven otherwise.
Recognise
- Thyroglossal cyst: MIDLINE, moves UP on tongue protrusion and swallowing (attached to the hyoid/tongue base), young patients
- Branchial cyst: smooth lump at the ANTERIOR border of sternocleidomastoid (upper third), young adults, may get infected
- Reactive lymph node: tender, mobile, resolves; the location and behaviour place the lump in a differential
Red flags
- A persistent, firm, fixed neck lump in an ADULT (especially with smoking/alcohol, dysphagia, hoarseness, or an HPV risk) → metastatic head-and-neck cancer/lymphoma → 2-week-wait
Differentials & how to tell them apart
Investigations
Ultrasound + FNA is the key initial work-up of a neck lump. Thyroglossal/branchial cysts are confirmed on imaging; a suspicious lump → 2-week-wait ENT, endoscopy, and look for a primary.
Management
Ultrasound + FNA to characterise; excise congenital cysts; 2-week-wait if suspicious
- 1Characterise the lump by location/behaviour and ultrasound + FNA. Congenital cysts (midline thyroglossal — moves on tongue protrusion; lateral branchial) → surgical excision.Gate: In an ADULT, a persistent neck lump is metastatic head-and-neck cancer or lymphoma until proven otherwise → ultrasound + FNA and 2-week-wait ENT, rather than assuming a benign cyst — congenital cysts are the young-patient diagnosis
- 2Thyroglossal cyst → Sistrunk procedure; branchial cyst → excision; malignant/lymphomatous nodes → oncology MDT after finding the primary.
Key points
Midline + moves on tongue protrusion = thyroglossal; lateral anterior to SCM = branchial. But in adults, treat a persistent neck lump as cancer until proven otherwise. Ultrasound + FNA is the workhorse.
Monitor & prognosis
Histology/cytology; recurrence after excision; cancer surveillance if malignant.
Excellent for congenital cysts; depends on diagnosis if malignant.
Source: NICE NG12; ENT UK