MLA Domain 5 · Presentation

Anaphylaxis

7 conditions in Finalist present this way. Work down the list and ask what would separate each one from the next — that discriminator is the exam question.

classic presentation · 1

Anaphylaxis

Any Airway/Breathing/Circulation compromise = anaphylaxis → IM adrenaline now; biphasic reaction (recurrence hours later

recognised feature · 6

Airway compromise / stridor

Exhaustion, cyanosis, falling GCS, silent chest = peri-arrest airway → immediate senior airway support

Cow milk protein allergy

Anaphylaxis (IgE); faltering growth

Primary immunodeficiency

SCID (severe combined immunodeficiency) in infancy → paediatric emergency (avoid live vaccines; needs transplant)

Shock

Cardiogenic or obstructive shock (raised JVP) — aggressive fluids can worsen it → treat the obstruction/pump cause

Shock — types & approach

Obstructive causes (tension pneumothorax, tamponade, massive PE) need immediate mechanical relief, not just fluids

Transfusion reactions

STOP the transfusion immediately for any significant reaction and reassess (ABCDE); recheck the patient/unit identity