Sexual health
AKT · Sexual health/Vaginitis / discharge

Vulvovaginal candidiasis

Candida albicans (yeast)

Overview

Common fungal vaginitis — itch and thick white discharge with a normal vaginal pH. Not an STI; precipitated by antibiotics, diabetes, pregnancy and immunosuppression.

Recognise

  • Thick white "cottage-cheese" discharge
  • Vulval ITCH and soreness, superficial dyspareunia, external dysuria
  • Erythema/fissuring; NORMAL vaginal pH (<4.5)

Red flags

  • Recurrent (≥4/year) → check diabetes/immunosuppression; pregnancy (oral azoles avoided)

Differentials & how to tell them apart

Bacterial vaginosisfishy odour, raised pH, no itch — opposite profile
Trichomoniasisfrothy green, raised pH, strawberry cervix
Contact/irritant dermatitisno discharge; exposure history

Investigations

Often clinical. Confirm with high vaginal swab if uncertain/recurrent; normal pH helps distinguish from BV/trichomonas.

Management

Fluconazole 150 mg oral capsule single dose

  1. 1Acute: fluconazole 150 mg oral single dose first-line.Gate: Oral fluconazole is contraindicated in pregnancy → use a clotrimazole 500 mg pessary (intravaginal)
  2. 2Pregnancy: topical imidazole (clotrimazole pessary ± cream); avoid oral azoles.
  3. 3Recurrent (≥4/yr): induction + maintenance azole regimen; investigate diabetes/immunosuppression.
Fluconazolefirst-line oral; 150 mg single dose; NOT in pregnancy
Clotrimazole pessaryintravaginal if oral contraindicated/pregnant; 500 mg single

Key points

Topical azoles can damage latex condoms/diaphragms. Recurrent disease → exclude diabetes.

Monitor & prognosis

Symptom resolution; recurrence work-up if frequent.

Benign; recurrences manageable.

Source: NICE CKS Candida - female genital (2025)