MLA Domain 5 · Presentation
Vomiting
30 conditions in Finalist present this way. Work down the list and ask what would separate each one from the next — that discriminator is the exam question.
classic presentation · 29
Painful red eye + haloes + nausea + fixed mid-dilated pupil = AACG — sight-threatening, refer immediately
Sepsis, gangrene/perforation, empyema → urgent surgery
ST elevation / new LBBB → primary PCI within 120 min of first medical contact (thrombolysis if PCI not available in time
Hypoglycaemia, coagulopathy, encephalopathy → fulminant hepatic failure; maternal and fetal emergency
Severe pancreatitis (Glasgow ≥3 / persistent organ failure) → HDU/ITU, high mortality
Refractory shock with low Na+ / high K+ / low glucose → give hydrocortisone without waiting for cortisol result
Symptomatic postural hypotension with falls; severe gastroparesis; coexisting cardiac autonomic involvement
Sepsis/mediastinitis → emergency resuscitation + surgery (high mortality, time-critical)
New seizure in an adult, progressive focal deficit, raised-ICP features → urgent imaging; impending herniation
Neonatal salt-wasting adrenal crisis — hyponatraemia + hyperkalaemia + hypoglycaemia + shock is a medical emergency
Reduced consciousness, shock, K+ <3.5 before insulin, severe acidosis (pH <7.1) → HDU/ICU
E. coli sepsis in a jaundiced neonate on milk → consider galactosaemia
Strangulation (tender, irreducible, red, painful lump + obstruction/peritonism) → emergency surgery
Severe dehydration, ketonuria, hyponatraemia/hypokalaemia → admit; consider Wernicke’s (give thiamine)
Acute mesenteric ischaemia (pain out of proportion + raised lactate ± AF) → emergency surgery/revascularisation — high m
Strangulation/ischaemia (constant pain, peritonism, fever, raised lactate) → emergency surgery
Significant/ongoing bleeding → endoscopic therapy
Choriocarcinoma (malignant GTD), thyroid storm, early/severe pre-eclampsia before 20 weeks
Acute abdomen with an adnexal mass — emergency; delay risks ovarian loss
Severe dehydration, electrolyte derangement → resuscitate BEFORE surgery
Falling GCS, a new fixed dilated pupil, Cushing reflex → impending herniation; neurosurgical emergency
Severe acidosis, very high levels, altered consciousness, seizures, renal failure → haemodialysis
It is a CLINICAL diagnosis → immediate surgical exploration; do NOT delay for an ultrasound — the testis infarcts within
Hypotension + multi-organ failure → emergency resuscitation/critical care
DKA (ketonaemia + acidosis + hyperglycaemia) → emergency (see acute care)
Shock, ongoing haematemesis, chronic liver disease (variceal), low Blatchford threshold for admission
Active variceal haemorrhage → major haemorrhage protocol; high mortality
Central features (HINTS exam suggesting stroke — direction-changing nystagmus, normal head-impulse test, skew deviation)
Apnoea/cyanosis in an infant; feeding difficulty → admit
recognised feature · 1